Polyethylene Oxide (PEO) High Molecular Weight Polymer | Sustained Release Matrix for Hydrophilic Tablets | USP/EP/ChP Compliant

Our Pharmaceutical Grade Polyethylene Oxide (PEO) is a high molecular weight, water-soluble nonionic homopolymer available in a wide range of viscosity grades (molecular weight from 100,000 to 7,000,000) . It serves as a versatile excipient for oral solid dosage forms. Key applications include: sustained-release matrix former (rapid hydration and gel formation for 10+ hours drug release) , mucoadhesive for buccal and gastro-retentive systems , binder for granulation and direct compression , and film-forming agent for thin films and medical device coatings . Conforms to USP-NF, EP, and ChP pharmacopoeias with CDE registration F20220000511 . Features fast hydration, high swelling capacity, thermoplastic properties, and nonionic nature (tasteless, colorless)

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Product Detail

Pharmaceutical Grade Polyethylene Oxide (PEO)

Product Overview

Polyethylene Oxide (PEO) is a nonionic homopolymer of ethylene oxide, represented by the formula H(OCH2CH2)nOH, where n represents the average number of oxyethylene groups ranging from approximately 2,000 to 200,000 . It is a high molecular weight, water-soluble polymer widely used as a pharmaceutical excipient in controlled release formulations, granulation binders, film coatings, and mucoadhesive drug delivery systems .

Product Identity:

Chemical Name: Polyethylene Oxide
CAS Number: 68441-17-8 / 25322-68-3
CDE Registration No.: F20220000511
Pharmacopoeia Compliance: ChP (CP2020), USP-NF, EP
Appearance: White to off-white, free-flowing powder with a slight ammonia odor
Solubility: Soluble in water and many common organic solvents (acetonitrile, chloroform, dichloromethane); insoluble in aliphatic hydrocarbons, ethylene glycol, and ethanol