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1500L Large Capacity Rapid Mixer Granulator | Industrial-Scale Wet Granulation for High-Volume Pharmaceutical Production

Our 1500L Rapid Mixer Granulator is engineered for large-scale industrial pharmaceutical production, offering an impressive working capacity of up to 1200L and batch output of 500-600 kg per cycle . This high-capacity granulation system integrates dry mixing, wet granulation, and particle densification in a single sealed vessel, delivering uniform, high-density granules with excellent flowability and compressibility. Constructed from 316L stainless steel with mirror-polished surfaces, it fully complies with GMP standards and features PLC touchscreen control, variable frequency drives for impeller and chopper, and optional CIP cleaning system. Ideal for pharmaceutical OSD (oral solid dosage) plants, nutraceutical manufacturers, and chemical industries requiring high-volume, batch-consistent granulation.

    Industrial 1500L Rapid Mixer Granulator for Large-Scale Pharmaceutical Production

    Product Overview

    The 1500L Rapid Mixer Granulator is our flagship industrial-scale granulation system, specifically engineered for high-volume pharmaceutical, nutraceutical, and chemical manufacturing facilities. Designed to meet the demanding requirements of commercial-scale production, this granulator delivers exceptional throughput, consistent granule quality, and reliable batch-to-batch reproducibility.

    With a gross volume of 1500L and working capacity of up to 1200L, this machine can process 500-600 kg of material per batch , making it ideal for manufacturers seeking to maximize production efficiency while maintaining stringent quality standards.

    Product Identity:

    • Equipment Type: Rapid Mixer Granulator (High Shear Wet Granulator)

    • Model Series: GHL-1500 / RMG-1500 (customizable)

    • Gross Volume: 1500 Liters

    • Working Capacity: 900-1200 Liters (60-80% of gross volume)

    • Batch Output: 500-600 kg per cycle (depending on material density)

    • Compliance: GMP, cGMP, CE, ISO 9001

    Key Features & Benefits

    1. Unmatched Large-Scale Production Capacity

    • 1500L gross volume – one of the largest capacities available for batch wet granulation

    • Processes 500-600 kg per batch – significantly reduces number of batches for high-volume production

    • Ideal for commercial manufacturing of blockbuster drugs and high-demand products

    • Short cycle time: complete dry mixing + wet granulation in 5-8 minutes per batch

    2. Superior Granule Quality

    • Produces uniform, spherical granules with excellent flowability and compressibility

    • Narrow particle size distribution (typically 20-80 mesh)

    • High granule density improves tablet compression performance

    • No delamination even with significant bulk density differences between API and excipients

    3. High-Efficiency Design

    • Complete processing in one sealed container – no material transfer losses

    • Variable frequency drives optimize power consumption

    • Pneumatic discharge ensures complete emptying with minimal residual material

    4. Robust GMP-Compliant Construction

    • All contact parts in 316L stainless steel with mirror polish (Ra ≤0.4μm)

    • No dead corners – easy cleaning and sanitization

    • Inflatable seals prevent material leakage and cross-contamination

    • Pneumatically operated discharge valve for efficient emptying

    • Optional CIP (Clean-in-Place) system available

    5. Advanced Automation & Control

    • PLC with HMI touchscreen for intuitive operation and recipe management

    • VFD (Variable Frequency Drive) for precise control of impeller and chopper speeds

    • Real-time monitoring of process parameters (temperature, amperage, time)

    • Data logging and batch reporting capabilities

    • Optional 21 CFR Part 11 compliant software for regulated environments

    6. Comprehensive Safety Features

    • Safety interlocks prevent operation when lid is open

    • Emergency stop buttons at multiple locations

    • Overload protection for motors

    • Optional explosion-proof configuration for solvent-based granulation

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