0102030405
Single Pot Multifunctional Top Drive Lab Rapid Mixer Granulator
Technical Specifications
Model: THG-10 (Lab Scale).
Capacity: 5L – 12L
Batch Capacity: 0.5kg to 5kg per batch (based on 0.5g/ml bulk density).
Mixing Impeller: 2.2 kW power, with variable speed control from 50–725 RPM.
Granulating Chopper: 0.75 kW power, with variable speed control from 300–2800 RPM.
Equipped with a precision peristaltic pump (0–150 RPM) for binder addition.
Integrated magnetic stirrer (200–1500 RPM) for precise binder solution preparation.
Utilities: Requires 380V/50Hz power supply; operational compressed air at 0.6–0.8 MPa.
Key Advantages
R&D-Specific Top-Drive Configuration:
Inherits the premium top-drive architecture of the industrial THG series, ensuring that the shaft seal is isolated from the product contact zone. This guarantees a clean, contamination-free environment for small-batch formulation development.
High-End Mechanical Components:
Built with industry-leading components, including ABB motors, NSK bearings, and Garlock shaft seals, ensuring the durability and precision required for critical R&D trials.
Versatile Process Capabilities:
- Integrated Magnetic Stirrer for binder solution conditioning.
- Advanced Vacuum Filtration & Pneumatic Purging for effective drying within the same vessel.
Scale-Up Predictive Design:
The impeller geometry and drive ratios are designed to correlate directly with industrial-scale machines, providing reliable data for seamless process scale-up.
Superior Containment & Safety:
Equipped with a dedicated stainless steel 304 explosion-proof cabinet, meeting the stringent safety requirements for handling sensitive or active research compounds.
Applications
The THG-10 is specifically engineered for laboratory and pilot-plant environments, offering:
Formulation Development:
Ideal for testing new granulation methods for high-potency or heat-sensitive compounds.
Process Parameter Optimization:
Allows for precise control of impeller/chopper speeds and binder addition rates to define the "Design Space" for complex drug products.
Small-Batch Manufacturing:
Bridges the gap between bench-top testing and pilot-scale production, suitable for clinical trial material manufacturing.
Advanced Granulation Research:
Fully capable of supporting specialized processes, including thermal melt granulation and effervescent tablet development.