High Containment AB Valve (Split Butterfly Valve) for Pharmaceutical Powder Transfer | OEB5 Level, 316L Stainless Steel, GMP Compliant

AB Valve (Split Butterfly Valve) for Pharmaceutical Containment Transfer

Product Overview

The AB Valve, also known as Split Butterfly Valve or αβ Valve, is a critical containment solution for the pharmaceutical, biotech, and chemical industries. It consists of two units: an active valve (mounted on mobile containers) and a passive valve (mounted on fixed equipment). When docked, they form a sealed connection that allows safe transfer of powders, granules, or sterile materials between containers without exposing the product or operators to contamination .

Our AB Valves are designed to meet the highest containment standards, achieving OEB5 level with dust leakage limits of OEL <1μg/m³, ensuring both product integrity and operator safety .

Key Features

1. Superior Containment Performance

• Achieves OEB5 containment level (OEL <1μg/m³)

• Metal-to-metal valve disc sealing for reliable closure 

• Optional vacuum system can improve isolation performance by an average of 35% 

2. High-Quality Materials

• Body material: 316L stainless steel, all product contact parts 

• Sealing materials: Food-grade FKM (FDA compliant) 

• Surface finish: Internal surface roughness Ra ≤0.4μm, mirror-polished, no dead corners 

• Bearings: PEEK material for durability and cleanability 

3. Advanced Design

• 180° symmetrical design for flexible docking positions 

• Active valve allows deviation up to ±14mm for easy alignment 

• Modular design of material contact components for easy replacement 

• Integrated buffer design for high valve matching precision 

4. Safety & Control Features

• Interlock function: Valve can only open when active and passive valves are fully mated 

• Multi-lock function prevents operation errors 

• Available in manual, pneumatic, or fully automatic operation 

5. Cleanability & Sterilization Options

• Optional CIP/SIP (Clean-in-Place / Sterilization-in-Place) capability 

• All seals withstand 121℃ steam sterilization 

• For standard models: manual cleaning of exposed surfaces meets regulatory requirements 

6. Customizable Specifications

• Standard sizes: DN50, 100, 150, 200, 250, 300 mm 

• Connections: Tri-Clamp (standard), PN6, PN10, ANSI#150 

• Custom sizes: Available upon request 

• Example: 8" (203.2mm) tri-clamp connection available 

Applications

Our AB Valves are widely used in:

Pharmaceutical & Biotech:

• Sterile API transfer and subpackaging 

• Isolator charging and discharging 

• Contained dispensing, charging, discharging, sampling, and milling 

• Sterile rubber plug containment transfer 

• High potency API (HPAPI) handling 

Other Industries:

• Chemical processing 

• Food and beverage production 

• Nuclear and CDC applications 

  Why Choose Our AB Valve?

  • Proven technology with mature quality control measures ensuring international first-class standards 

  • Customizable solutions for various usage nodes of complete closed production lines 

  • Full documentation including material certificates, surface finish reports, and validation support 

  • Global compliance meeting the latest GMP, FDA, and EU requirements 

  • Comprehensive support from design consultation to after-sales service